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    PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 [ Manis javanica (Malayan pangolin) ]

    Gene ID: 108384981, updated on 14-Mar-2024

    Summary

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    Gene symbol
    PRKAA2
    Gene description
    protein kinase AMP-activated catalytic subunit alpha 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Manis javanica
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
    Orthologs
    human mouse all
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    Genomic context

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    See PRKAA2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023436069.1 (12491812..12538445)
    100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016553818.1 (8209..29436)

    NW_023436069.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108391869 Neighboring gene phospholipid phosphatase 3 Neighboring gene 5'-AMP-activated protein kinase catalytic subunit alpha-2-like Neighboring gene uncharacterized LOC118973029 Neighboring gene FYN binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5'-AMP-activated protein kinase catalytic subunit alpha-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference YNU_ManJav_2.0 Primary Assembly

    Genomic

    1. NW_023436069.1 Reference YNU_ManJav_2.0 Primary Assembly

      Range
      12491812..12538445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_037021950.1 → XP_036877845.1  5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1

      Conserved Domains (3) summary
      cd12200
      Location:395 → 550
      AMPKA2_C; C-terminal regulatory domain of 5'-AMP-activated serine/threonine kinase, subunit alpha
      cd14404
      Location:285 → 349
      UBA_AID_AAPK2; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPKalpha-2)
      cd14079
      Location:13 → 268
      STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase

    2. XM_037021951.1 → XP_036877846.1  5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X2

      Conserved Domains (3) summary
      cd12200
      Location:305 → 460
      AMPKA2_C; C-terminal regulatory domain of 5'-AMP-activated serine/threonine kinase, subunit alpha
      cd14404
      Location:195 → 259
      UBA_AID_AAPK2; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPKalpha-2)
      cl21453
      Location:1 → 178
      PKc_like; Protein Kinases, catalytic domain

    3. XM_017642236.2 → XP_017497725.1  5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X2

      Conserved Domains (3) summary
      cd12200
      Location:305 → 460
      AMPKA2_C; C-terminal regulatory domain of 5'-AMP-activated serine/threonine kinase, subunit alpha
      cd14404
      Location:195 → 259
      UBA_AID_AAPK2; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPKalpha-2)
      cl21453
      Location:1 → 178
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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