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    PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [ Thamnophis sirtalis ]

    Gene ID: 106550043, updated on 13-Mar-2024

    Summary

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    Gene symbol
    PFKFB4
    Gene description
    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Thamnophis sirtalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Natricinae; Thamnophis
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See PFKFB4 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    100 current Thamnophis_sirtalis-6.0 (GCF_001077635.1) Unplaced Scaffold NW_013659113.1 (186726..226949)

    NW_013659113.1Genomic Context describing neighboring genes Neighboring gene ceramide kinase Neighboring gene peroxisomal biogenesis factor 7 Neighboring gene protein kinase C delta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_013659113.1 Unplaced Scaffold Reference Thamnophis_sirtalis-6.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 6-phosphofructo-2-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fructose 2,6-bisphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Thamnophis sirtalis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Thamnophis_sirtalis-6.0

    Genomic

    1. NW_013659113.1 Reference Thamnophis_sirtalis-6.0

      Range
      186726..226949
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014067822.1 → XP_013923297.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

      UniProtKB/TrEMBL
      A0A6I9YGJ1
      Conserved Domains (2) summary
      pfam00300
      Location:254 → 440
      His_Phos_1; Histidine phosphatase superfamily (branch 1)
      pfam01591
      Location:32 → 251
      6PF2K; 6-phosphofructo-2-kinase
    Nucleotide Protein
    Heading Accession and Version

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