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    hic1 hypermethylated in cancer 1 [ Fundulus heteroclitus (mummichog) ]

    Gene ID: 105934543, updated on 20-Aug-2024

    Summary

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    Gene symbol
    hic1
    Gene description
    hypermethylated in cancer 1
    See related
    EnsemblRapid:ENSFHEG00000003606
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Fundulus heteroclitus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Fundulidae; Fundulus
    Orthologs
    human zebrafish all
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    Genomic context

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    See hic1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    102 current MU-UCD_Fhet_4.1 (GCF_011125445.2) 18 NC_046378.1 (27766788..27782634)
    101 previous assembly Fundulus_heteroclitus-3.0.2 (GCF_000826765.1) Unplaced Scaffold NW_012234404.1 (247857..263947)

    Chromosome 18 - NC_046378.1Genomic Context describing neighboring genes Neighboring gene TAO kinase 1a Neighboring gene TSR1 ribosome maturation factor Neighboring gene uncharacterized LOC118566736 Neighboring gene diphthamide biosynthesis 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hypermethylated in cancer 1 protein
    Names
    B-cell lymphoma 6 protein
    HIC ZBTB transcriptional repressor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Fundulus heteroclitus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference MU-UCD_Fhet_4.1 Primary Assembly

    Genomic

    1. NC_046378.1 Reference MU-UCD_Fhet_4.1 Primary Assembly

      Range
      27766788..27782634
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012874590.3 → XP_012730044.2  hypermethylated in cancer 1 protein isoform X3

      UniProtKB/TrEMBL
      A0A3Q2NU14
      Related
      ENSFHEP00000062167.1, ENSFHET00000046074.1
      Conserved Domains (4) summary
      sd00017
      Location:551 → 571
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18333
      Location:7 → 129
      BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)
      pfam00096
      Location:549 → 571
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:591 → 616
      zf-H2C2_2; Zinc-finger double domain

    2. XM_012874589.3 → XP_012730043.2  hypermethylated in cancer 1 protein isoform X1

      UniProtKB/TrEMBL
      A0A3Q2NU14
      Related
      ENSFHEP00000002789.2, ENSFHET00000011641.2
      Conserved Domains (4) summary
      sd00017
      Location:574 → 594
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18333
      Location:30 → 152
      BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)
      pfam00096
      Location:572 → 594
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:614 → 639
      zf-H2C2_2; Zinc-finger double domain

    3. XM_036150298.1 → XP_036006191.1  hypermethylated in cancer 1 protein isoform X2

      UniProtKB/TrEMBL
      A0A3Q2NU14
      Conserved Domains (4) summary
      sd00017
      Location:564 → 584
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18333
      Location:20 → 142
      BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)
      pfam00096
      Location:562 → 584
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:604 → 629
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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