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    TJP2 tight junction protein 2 [ Pterocles gutturalis (yellow-throated sandgrouse) ]

    Gene ID: 104458514, updated on 3-Aug-2024

    Summary

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    Gene symbol
    TJP2
    Gene description
    tight junction protein 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pterocles gutturalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Columbimorphae; Pterocliformes; Pteroclidae; Pterocles
    Orthologs
    human mouse all
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    Genomic context

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    See TJP2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    100 current ASM69924v1 (GCF_000699245.1) Unplaced Scaffold NW_010140286.1 (1315..27691, complement)

    NW_010140286.1Genomic Context describing neighboring genes

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_010140286.1 Unplaced Scaffold Reference ASM69924v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell junction organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of endothelial intestinal barrier IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of blood-brain barrier permeability IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tight junction protein ZO-2
    Names
    Tight junction protein ZO-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Pterocles gutturalis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM69924v1

    Genomic

    1. NW_010140286.1 Reference ASM69924v1

      Range
      1315..27691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010083568.1 → XP_010081870.1  tight junction protein ZO-2 isoform X1

      Conserved Domains (4) summary
      cd12027
      Location:600 → 662
      SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
      smart00072
      Location:696 → 875
      GuKc; Guanylate kinase homologues
      smart00228
      Location:300 → 378
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:36 → 121
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    2. XM_010083569.1 → XP_010081871.1  tight junction protein ZO-2 isoform X2

      Conserved Domains (4) summary
      cd12027
      Location:573 → 635
      SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
      smart00072
      Location:669 → 848
      GuKc; Guanylate kinase homologues
      smart00228
      Location:273 → 351
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:9 → 94
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    Nucleotide Protein
    Heading Accession and Version

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