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    CAPN3 calpain 3 [ Nipponia nippon (crested ibis) ]

    Gene ID: 104020344, updated on 3-Aug-2024

    Summary

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    Gene symbol
    CAPN3
    Gene description
    calpain 3
    Locus tag
    Y956_16606
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nipponia nippon
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Pelecaniformes; Threskiornithidae; Nipponia
    Also known as
    Calpain-3
    Orthologs
    human mouse all
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    Genomic context

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    See CAPN3 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    100 current ASM70822v1 (GCF_000708225.1) Unplaced Scaffold NW_009002855.1 (5819702..5853637, complement)

    NW_009002855.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 23 Neighboring gene zinc finger protein 106 Neighboring gene glucosidase alpha, neutral C Neighboring gene transmembrane protein 87A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_009002855.1 Unplaced Scaffold Reference ASM70822v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calpain-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Nipponia nippon Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM70822v1 Primary Assembly

    Genomic

    1. NW_009002855.1 Reference ASM70822v1 Primary Assembly

      Range
      5819702..5853637 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009473760.1 → XP_009472035.1  calpain-3

      UniProtKB/TrEMBL
      A0A091VXH3
      Conserved Domains (5) summary
      cd00051
      Location:687 → 741
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00648
      Location:70 → 409
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:423 → 573
      Calpain_III; Calpain large subunit, domain III
      pfam13499
      Location:718 → 774
      EF-hand_7; EF-hand domain pair
      pfam16648
      Location:577 → 643
      Calpain_u2; Unstructured region on Calpain-3
    Nucleotide Protein
    Heading Accession and Version

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