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    CRKL CRK like proto-oncogene, adaptor protein [ Galeopterus variegatus (Sunda flying lemur) ]

    Gene ID: 103592708, updated on 11-Mar-2024

    Summary

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    Gene symbol
    CRKL
    Gene description
    CRK like proto-oncogene, adaptor protein
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Galeopterus variegatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Dermoptera; Cynocephalidae; Galeopterus
    Orthologs
    human mouse all
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    Genomic context

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    See CRKL in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    100 current G_variegatus-3.0.2 (GCF_000696425.1) Unplaced Scaffold NW_007727315.1 (77432..111140, complement)

    NW_007727315.1Genomic Context describing neighboring genes Neighboring gene THAP domain containing 7 Neighboring gene leucine zipper like post translational regulator 1 Neighboring gene activating signal cointegrator 1 complex subunit 2 Neighboring gene cytochrome b-c1 complex subunit 9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_007727315 unplaced scaffold reference G_variegatus-3.0.2 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    crk-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Galeopterus variegatus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference G_variegatus-3.0.2 Primary Assembly

    Genomic

    1. NW_007727315.1 Reference G_variegatus-3.0.2 Primary Assembly

      Range
      77432..111140 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008575528.1 → XP_008573750.1  crk-like protein

      Conserved Domains (3) summary
      cd09926
      Location:6 → 106
      SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
      cd11758
      Location:126 → 180
      SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
      cd11759
      Location:237 → 293
      SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    Nucleotide Protein
    Heading Accession and Version

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