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    PLCZ1 phospholipase C zeta 1 [ Chlorocebus sabaeus (green monkey) ]

    Gene ID: 103218714, updated on 11-Mar-2024

    Summary

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    Gene symbol
    PLCZ1
    Gene description
    phospholipase C zeta 1
    See related
    Ensembl:ENSCSAG00000008141
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Chlorocebus sabaeus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
    Orthologs
    human mouse all
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    Genomic context

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    See PLCZ1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666069.1 (16626501..16679788)
    100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 11 NC_023652.1 (18534672..18587756, complement)

    NW_023666069.1Genomic Context describing neighboring genes Neighboring gene BLOC-1-related complex subunit 8-like Neighboring gene capping actin protein of muscle Z-line subunit alpha 3 Neighboring gene phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma Neighboring gene zinc finger CCHC domain-containing protein 9-like Neighboring gene dnaJ homolog subfamily C member 8-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration involved in egg activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Vero_WHO_p1.0

    Genomic

    1. NW_023666069.1 Reference Vero_WHO_p1.0

      Range
      16626501..16679788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_007967800.2 → XP_007965991.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X1

      UniProtKB/TrEMBL
      A0A0D9R6Y3
      Related
      ENSCSAP00000004372.1
      Conserved Domains (4) summary
      cd00275
      Location:481 → 606
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08595
      Location:154 → 452
      PI-PLCc_zeta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-zeta
      PLN02952
      Location:71 → 607
      PLN02952; phosphoinositide phospholipase C
      pfam09279
      Location:72 → 154
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

    2. XM_007967801.2 → XP_007965992.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X2

      UniProtKB/TrEMBL
      A0A0D9R6Y3
      Conserved Domains (3) summary
      cd00275
      Location:377 → 502
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08595
      Location:50 → 348
      PI-PLCc_zeta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-zeta
      pfam09279
      Location:1 → 50
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

    3. XM_037990305.1 → XP_037846233.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X3

      Conserved Domains (4) summary
      PLN02952
      Location:44 → 414
      PLN02952; phosphoinositide phospholipase C
      cd15898
      Location:1 → 32
      EFh_PI-PLC; EF-hand motif [structural motif]
      cl28895
      Location:1 → 48
      EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
      cl14615
      Location:35 → 259
      PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    Nucleotide Protein
    Heading Accession and Version

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