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    CHRNE cholinergic receptor nicotinic epsilon subunit [ Vicugna pacos (alpaca) ]

    Gene ID: 102538216, updated on 10-Mar-2024

    Summary

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    Gene symbol
    CHRNE
    Gene description
    cholinergic receptor nicotinic epsilon subunit
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Vicugna pacos
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Vicugna
    Orthologs
    human mouse all
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    Genomic context

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    See CHRNE in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    102 current VicPac3.1 (GCF_000164845.3) Unplaced Scaffold NW_022038907.1 (1276637..1291645)
    101 previous assembly Vicugna_pacos-2.0.1 (GCF_000164845.1) Unplaced Scaffold NW_005883004.1 (187696..192252, complement)

    NW_022038907.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 11 Neighboring gene glycoprotein Ib platelet subunit alpha Neighboring gene transfer RNA alanine (anticodon UGC) Neighboring gene chromosome unknown C17orf107 homolog Neighboring gene misshapen like kinase 1 Neighboring gene phospholipase D2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholine-gated monoatomic cation-selective channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acetylcholine receptor subunit epsilon
    Names
    cholinergic receptor, nicotinic, epsilon (muscle)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Vicugna pacos Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference VicPac3.1 Primary Assembly

    Genomic

    1. NW_022038907.1 Reference VicPac3.1 Primary Assembly

      Range
      1276637..1291645
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031674927.1 → XP_031530787.1  acetylcholine receptor subunit epsilon isoform X1

      UniProtKB/TrEMBL
      A0A6J3AC40
      Conserved Domains (3) summary
      cd03558
      Location:243 → 257
      LGIC_ECD; Cys-loop [structural motif]
      cl28912
      Location:144 → 343
      LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
      pfam02932
      Location:351 → 577
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    2. XM_031674928.1 → XP_031530788.1  acetylcholine receptor subunit epsilon isoform X2

      UniProtKB/TrEMBL
      A0A6J3AAW7
      Conserved Domains (3) summary
      cd03558
      Location:243 → 257
      LGIC_ECD; Cys-loop [structural motif]
      cl28912
      Location:144 → 334
      LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
      pfam02932
      Location:342 → 568
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    3. XM_031674929.1 → XP_031530789.1  acetylcholine receptor subunit epsilon isoform X3

      UniProtKB/TrEMBL
      A0A6J3AAL0
      Conserved Domains (3) summary
      cd03558
      Location:148 → 162
      LGIC_ECD; Cys-loop [structural motif]
      cl28912
      Location:49 → 248
      LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
      pfam02932
      Location:256 → 482
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    4. XM_006217570.3 → XP_006217632.1  acetylcholine receptor subunit epsilon isoform X4

      UniProtKB/TrEMBL
      A0A6I9IPA6
      Conserved Domains (3) summary
      cd03558
      Location:148 → 162
      LGIC_ECD; Cys-loop [structural motif]
      cl28912
      Location:49 → 239
      LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
      pfam02932
      Location:247 → 473
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    5. XM_031674930.1 → XP_031530790.1  acetylcholine receptor subunit epsilon isoform X5

      UniProtKB/TrEMBL
      A0A6J3A917
      Conserved Domains (2) summary
      cl28912
      Location:80 → 166
      LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
      pfam02932
      Location:174 → 400
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
    Nucleotide Protein
    Heading Accession and Version

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