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    Smad3 SMAD family member 3 [ Ictidomys tridecemlineatus (thirteen-lined ground squirrel) ]

    Gene ID: 101973097, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Smad3
    Gene description
    SMAD family member 3
    Locus tag
    H1C71_017034
    See related
    EnsemblRapid:ENSSTOG00015013726
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ictidomys tridecemlineatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current HiC_Itri_2 (GCF_016881025.1) Unplaced Scaffold NW_024408640.1 (109232767..109341735)
    102 previous assembly SpeTri2.0 (GCF_000236235.1) Unplaced Scaffold NW_004936471.1 (27080662..27185861)

    NW_024408640.1Genomic Context describing neighboring genes Neighboring gene mitochondrial proton/calcium exchanger protein-like Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC110597985 Neighboring gene uncharacterized LOC120886359 Neighboring gene alpha and gamma adaptin binding protein Neighboring gene uncharacterized LOC120886358 Neighboring gene IQ motif containing H

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heteromeric SMAD protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mothers against decapentaplegic homolog 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Ictidomys tridecemlineatus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HiC_Itri_2 Primary Assembly

    Genomic

    1. NW_024408640.1 Reference HiC_Itri_2 Primary Assembly

      Range
      109232767..109341735
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005316724.4 → XP_005316781.1  mothers against decapentaplegic homolog 3 isoform X1

      See identical proteins and their annotated locations for XP_005316781.1

      UniProtKB/TrEMBL
      I3MF72
      Related
      ENSSTOP00015016779.1, ENSSTOT00015018396.1
      Conserved Domains (2) summary
      cd10491
      Location:8 → 132
      MH1_SMAD_2_3; N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3
      cd10985
      Location:224 → 414
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3

    2. XM_040275168.1 → XP_040131102.1  mothers against decapentaplegic homolog 3 isoform X3

      Conserved Domains (2) summary
      cd10985
      Location:119 → 309
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:1 → 27
      MH1; N-terminal Mad Homology 1 (MH1) domain

    3. XM_040275167.1 → XP_040131101.1  mothers against decapentaplegic homolog 3 isoform X2

      Conserved Domains (2) summary
      cd10985
      Location:167 → 357
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:12 → 75
      MH1; N-terminal Mad Homology 1 (MH1) domain
    Nucleotide Protein
    Heading Accession and Version

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