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    usp8 ubiquitin specific peptidase 8 [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 101172642, updated on 8-Mar-2024

    Summary

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    Gene symbol
    usp8
    Gene description
    ubiquitin specific peptidase 8
    See related
    EnsemblRapid:ENSORLG00000003140
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Orthologs
    human zebrafish all
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    Genomic context

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    See usp8 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 3 NC_019861.2 (13662398..13674680, complement)
    102 previous assembly ASM31367v1 (GCF_000313675.1) 3 NC_019861.1 (11958406..11970152, complement)

    Chromosome 3 - NC_019861.2Genomic Context describing neighboring genes Neighboring gene LEO1 homolog, Paf1/RNA polymerase II complex component Neighboring gene mitogen-activated protein kinase 6 Neighboring gene ubiquitin specific peptidase 50 Neighboring gene very long-chain acyl-CoA synthetase Neighboring gene histidine decarboxylase Neighboring gene very long-chain acyl-CoA synthetase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K63-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019861.2 Reference ASM223467v1 Primary Assembly

      Range
      13662398..13674680 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011488556.3 → XP_011486858.1  ubiquitin carboxyl-terminal hydrolase 8

      UniProtKB/TrEMBL
      A0A3P9MNP3, H2LDA8
      Related
      ENSORLP00000003910.3, ENSORLT00000003911.3
      Conserved Domains (4) summary
      smart00450
      Location:197 → 310
      RHOD; Rhodanese Homology Domain
      pfam00443
      Location:746 → 1075
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam08969
      Location:7 → 115
      USP8_dimer; USP8 dimerisation domain
      cl25751
      Location:358 → 620
      DUF4045; Domain of unknown function (DUF4045)

    2. XM_020712607.2 → XP_020568266.1  ubiquitin carboxyl-terminal hydrolase 8

      UniProtKB/TrEMBL
      A0A3P9MNP3, H2LDA8
      Related
      ENSORLP00000058133.1, ENSORLT00000081200.1
      Conserved Domains (4) summary
      smart00450
      Location:197 → 310
      RHOD; Rhodanese Homology Domain
      pfam00443
      Location:746 → 1075
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam08969
      Location:7 → 115
      USP8_dimer; USP8 dimerisation domain
      cl25751
      Location:358 → 620
      DUF4045; Domain of unknown function (DUF4045)
    Nucleotide Protein
    Heading Accession and Version

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