U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    HFE homeostatic iron regulator [ Gorilla gorilla gorilla (western lowland gorilla) ]

    Gene ID: 101126285, updated on 6-Jun-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    HFE
    Gene description
    homeostatic iron regulator
    See related
    Ensembl:ENSGGOG00000006373
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gorilla gorilla gorilla (sub-species: gorilla)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See HFE in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 5 NC_073229.2 (43773207..43784323)
    RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 6 NC_073230.1 (43560694..43570124)

    Chromosome 5 - NC_073229.2Genomic Context describing neighboring genes Neighboring gene histone H2B type 1-B Neighboring gene H1.2 linker histone, cluster member Neighboring gene histone H4-like Neighboring gene H1.6 linker histone, cluster member

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables peptide antigen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transferrin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in antigen processing and presentation of endogenous peptide antigen via MHC class Ib IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell mediated cytotoxicity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of iron ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to iron ion starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    hereditary hemochromatosis protein
    Names
    hemochromatosis

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Genomic

    1. NC_073229.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

      Range
      43773207..43784323
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063707405.1 → XP_063563475.1  hereditary hemochromatosis protein isoform X1

      UniProtKB/TrEMBL
      A0A2I2Z8I9, G3QU39

    2. XM_063707406.1 → XP_063563476.1  hereditary hemochromatosis protein isoform X2

      UniProtKB/TrEMBL
      A0A2I2ZT71

    RNA

    1. XR_010134218.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.