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    HFE homeostatic iron regulator [ Gorilla gorilla gorilla (western lowland gorilla) ]

    Gene ID: 101126285, updated on 10-Oct-2024

    Summary

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    Gene symbol
    HFE
    Gene description
    homeostatic iron regulator
    See related
    Ensembl:ENSGGOG00000006373
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gorilla gorilla gorilla (sub-species: gorilla)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
    Orthologs
    human mouse all
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    Genomic context

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    See HFE in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 5 NC_073229.2 (43773207..43784323)
    RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 6 NC_073230.1 (43560694..43570124)

    Chromosome 5 - NC_073229.2Genomic Context describing neighboring genes Neighboring gene histone H2B type 1-B Neighboring gene H1.2 linker histone, cluster member Neighboring gene histone H4-like Neighboring gene H1.6 linker histone, cluster member

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables peptide antigen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transferrin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in antigen processing and presentation of endogenous peptide antigen via MHC class Ib IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell mediated cytotoxicity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of iron ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to iron ion starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hereditary hemochromatosis protein
    Names
    hemochromatosis

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Genomic

    1. NC_073229.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

      Range
      43773207..43784323
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063707405.1 → XP_063563475.1  hereditary hemochromatosis protein isoform X1

      UniProtKB/TrEMBL
      G3QU39

    2. XM_063707406.1 → XP_063563476.1  hereditary hemochromatosis protein isoform X2

      UniProtKB/TrEMBL
      A0A2I2ZT71

    RNA

    1. XR_010134218.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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