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    LPCAT2 lysophosphatidylcholine acyltransferase 2 [ Ovis aries (sheep) ]

    Gene ID: 101115816, updated on 8-Mar-2024

    Summary

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    Gene symbol
    LPCAT2
    Gene description
    lysophosphatidylcholine acyltransferase 2
    See related
    EnsemblRapid:ENSOARG00020008951
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See LPCAT2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 14 NC_056067.1 (23280672..23351095)

    Chromosome 14 - NC_056067.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132657677 Neighboring gene matrix metallopeptidase 2 Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene calpain small subunit 2 Neighboring gene uncharacterized LOC121816483 Neighboring gene transfer RNA phenylalanine (anticodon GAA) Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene solute carrier family 6 member 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056067.1 Chromosome 14 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-acylglycerophosphocholine O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysophosphatidylcholine acyltransferase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056067.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      23280672..23351095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004014990.6 → XP_004015039.1  lysophosphatidylcholine acyltransferase 2 isoform X1

      See identical proteins and their annotated locations for XP_004015039.1

      UniProtKB/TrEMBL
      A0A6P3EJE1, W5Q9N1
      Related
      ENSOARP00020039310.1, ENSOART00020056663.1
      Conserved Domains (4) summary
      cd07991
      Location:117 → 327
      LPLAT_LPCAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like
      cd00051
      Location:396 → 458
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd15897
      Location:325 → 361
      EFh_PEF; EF-hand motif [structural motif]
      cl25352
      Location:324 → 448
      EFh_PEF; The penta-EF hand (PEF) family

    2. XM_042231639.2 → XP_042087573.1  lysophosphatidylcholine acyltransferase 2 isoform X2

      Conserved Domains (4) summary
      cd07991
      Location:117 → 327
      LPLAT_LPCAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like
      cd00051
      Location:396 → 458
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd15897
      Location:392 → 431
      EFh_PEF; EF-hand motif [structural motif]
      cl25352
      Location:324 → 448
      EFh_PEF; The penta-EF hand (PEF) family

    3. XM_042231640.2 → XP_042087574.1  lysophosphatidylcholine acyltransferase 2 isoform X3

      Conserved Domains (2) summary
      cd07991
      Location:117 → 327
      LPLAT_LPCAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like
      cl08302
      Location:383 → 425
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    Nucleotide Protein Strain
    Heading Accession and Version

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