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    GCLC glutamate-cysteine ligase catalytic subunit [ Otolemur garnettii (small-eared galago) ]

    Gene ID: 100959223, updated on 8-Mar-2024

    Summary

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    Gene symbol
    GCLC
    Gene description
    glutamate-cysteine ligase catalytic subunit
    See related
    Ensembl:ENSOGAG00000007018
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Otolemur garnettii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
    Orthologs
    human mouse all
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    Genomic context

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    See GCLC in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852430.1 (2224746..2268124, complement)

    NW_003852430.1Genomic Context describing neighboring genes Neighboring gene ELOVL fatty acid elongase 5 Neighboring gene cytochrome b-c1 complex subunit 2, mitochondrial-like Neighboring gene L-threonine 3-dehydrogenase, mitochondrial-like Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_003852430 Unplaced Scaffold Reference OtoGar3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutamate-cysteine ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of glutamate-cysteine ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate--cysteine ligase catalytic subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference OtoGar3

    Genomic

    1. NW_003852430.1 Reference OtoGar3

      Range
      2224746..2268124 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003789650.3 → XP_003789698.1  glutamate--cysteine ligase catalytic subunit

      UniProtKB/TrEMBL
      H0WVF1
      Related
      ENSOGAP00000006285.2, ENSOGAT00000007023.2
      Conserved Domains (1) summary
      pfam03074
      Location:236 → 608
      GCS; Glutamate-cysteine ligase
    Nucleotide Protein
    Heading Accession and Version

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