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    GH1 growth hormone 1 [ Capra hircus (goat) ]

    Gene ID: 100861230, updated on 16-Nov-2023

    Summary

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    Gene symbol
    GH1
    Gene description
    growth hormone 1
    See related
    EnsemblRapid:ENSCHIG00000018669
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Capra hircus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
    Also known as
    GH; GH4; GH5; GH-4; GH-5
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    Genomic context

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    See GH1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    102 current ASM170441v1 (GCF_001704415.1) 19 NC_030826.1 (47735339..47736972, complement)
    101 previous assembly CHIR_1.0 (GCF_000317765.1) 19 NC_022311.1 (47266042..47267410, complement)

    Chromosome 19 - NC_030826.1Genomic Context describing neighboring genes Neighboring gene intercellular adhesion molecule 5 Neighboring gene somatotropin-like Neighboring gene CD79b molecule Neighboring gene sodium voltage-gated channel alpha subunit 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effect of growth hormone gene polymorphism on growth traits in migratory Gaddi goats of Western Himalayas, India. Gitanjli G, et al. Trop Anim Health Prod, 2020 Jul. PMID 32052250
    2. Growth hormone gene variability and its effects on milk traits in primiparous Sarda goats. Dettori ML, et al. J Dairy Res, 2013 Aug. PMID 23611522
    3. Nucleotide sequence of the growth hormone gene cDNA from goat Capra hircus L. (Tokara). Yato M, et al. Nucleic Acids Res, 1988 Apr 25. PMID 3375065, Free PMC Article
    4. Cloning and sequencing of cDNA that encodes goat growth hormone. Yamano Y, et al. FEBS Lett, 1988 Feb 15. PMID 3342884
    5. Variation in sequences and mRNA expression levels of growth hormone (GH), insulin-like growth factor I (IGF-I) and II (IGF-II) genes between prolific Lezhi black goat and non-prolific Tibetan goat (Capra hircus). Zi XD, et al. Gen Comp Endocrinol, 2013 Jun 15. PMID 23578901

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Effect of growth hormone gene polymorphism on growth traits in migratory Gaddi goats of Western Himalayas, India.
      Title: Effect of growth hormone gene polymorphism on growth traits in migratory Gaddi goats of Western Himalayas, India.
    2. genetic variation and milk production and composition
      Title: Growth hormone gene variability and its effects on milk traits in primiparous Sarda goats.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables growth hormone receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in growth hormone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to nutrient levels IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    somatotropin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001285586.1 → NP_001272515.1  somatotropin precursor

      See identical proteins and their annotated locations for NP_001272515.1

      Status: PROVISIONAL

      Source sequence(s)
      JX570671
      UniProtKB/Swiss-Prot
      P01247, P07289, P67931, Q29404
      UniProtKB/TrEMBL
      A0A1D8RIS9, A0A3G2B835, A0A452E818, F8UL30, Q19AP0
      Related
      ENSCHIP00000019867.2, ENSCHIT00000027690.2
      Conserved Domains (1) summary
      cd10285
      Location:36 → 215
      somatotropin_like; Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones

    RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM170441v1 Primary Assembly

    Genomic

    1. NC_030826.1 Reference ASM170441v1 Primary Assembly

      Range
      47735339..47736972 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P67931.1 GenPept UniProtKB/Swiss-Prot:P67931

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.