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    GUCY2D guanylate cyclase 2D, retinal [ Sus scrofa (pig) ]

    Gene ID: 100625536, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GUCY2Dprovided by VGNC
    Official Full Name
    guanylate cyclase 2D, retinalprovided by VGNC
    Primary source
    VGNC:VGNC:88753
    See related
    Ensembl:ENSSSCG00000025345
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in ovary (RPKM 1.3), lung (RPKM 1.0) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See GUCY2D in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (53200570..53250566)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (55602395..55617678)

    Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100525078 Neighboring gene potassium voltage-gated channel subfamily A regulatory beta subunit 3 Neighboring gene trafficking protein particle complex subunit 1 Neighboring gene centrobin, centriole duplication and spindle assembly protein Neighboring gene arachidonate 15-lipoxygenase type B Neighboring gene arachidonate 15-lipoxygenase B-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanylate cyclase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cGMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in receptor guanylyl cyclase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    retinal guanylyl cyclase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

      Range
      53200570..53250566
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021067848.1 → XP_020923507.1  retinal guanylyl cyclase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8D1RFI5, A0A8D1W877, I3LJL1
      Related
      ENSSSCP00000024272.2, ENSSSCT00000029871.4
      Conserved Domains (4) summary
      smart00044
      Location:847 → 1039
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cd14043
      Location:539 → 814
      PK_GC-2D; Pseudokinase domain of the membrane Guanylate Cyclase receptor, GC-2D
      pfam07701
      Location:823 → 868
      HNOBA; Heme NO binding associated
      cl10011
      Location:58 → 434
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

    2. XM_021067847.1 → XP_020923506.1  retinal guanylyl cyclase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8D1RFI5, A0A8D1W877
      Conserved Domains (4) summary
      smart00044
      Location:875 → 1067
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cd14043
      Location:567 → 842
      PK_GC-2D; Pseudokinase domain of the membrane Guanylate Cyclase receptor, GC-2D
      pfam07701
      Location:851 → 896
      HNOBA; Heme NO binding associated
      cl10011
      Location:58 → 462
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

    3. XM_021067849.1 → XP_020923508.1  retinal guanylyl cyclase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8D1RFI5, A0A8D1W877
      Conserved Domains (4) summary
      smart00044
      Location:875 → 1067
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cd14043
      Location:567 → 842
      PK_GC-2D; Pseudokinase domain of the membrane Guanylate Cyclase receptor, GC-2D
      pfam07701
      Location:851 → 896
      HNOBA; Heme NO binding associated
      cl10011
      Location:58 → 462
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein
    Heading Accession and Version

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