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    STAT2 signal transducer and activator of transcription 2 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

    Gene ID: 100585171, updated on 11-Apr-2024

    Summary

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    Gene symbol
    STAT2
    Gene description
    signal transducer and activator of transcription 2
    See related
    EnsemblRapid:ENSNLEG00000017494
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nomascus leucogenys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
    Orthologs
    human mouse all
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    Genomic context

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    See STAT2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Asia_NLE_v1 (GCF_006542625.1) 11 NC_044391.1 (54910804..54930541)
    102 previous assembly Nleu_3.0 (GCF_000146795.2) 11 NC_019826.1 (56439794..56473784)

    Chromosome 11 - NC_044391.1Genomic Context describing neighboring genes Neighboring gene timeless circadian regulator Neighboring gene U7 small nuclear RNA Neighboring gene apolipoprotein F Neighboring gene interleukin 23 subunit alpha Neighboring gene poly(A) specific ribonuclease subunit PAN2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to peptide hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in type I interferon-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal transducer and activator of transcription 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Asia_NLE_v1 Primary Assembly

    Genomic

    1. NC_044391.1 Reference Asia_NLE_v1 Primary Assembly

      Range
      54910804..54930541
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003252812.2 → XP_003252860.1  signal transducer and activator of transcription 2 isoform X1

      UniProtKB/TrEMBL
      A0A2I3G1P6, G1S6V0
      Related
      ENSNLEP00000021239.1, ENSNLET00000022315.3
      Conserved Domains (5) summary
      cd10373
      Location:556 → 706
      SH2_STAT2; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 2 proteins
      smart00964
      Location:2 → 124
      STAT_int; STAT protein, protein interaction domain
      cd16852
      Location:141 → 312
      STAT2_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 2 (STAT2)
      cl28920
      Location:316 → 475
      STAT_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription (STAT)
      pfam12188
      Location:786 → 838
      STAT2_C; Signal transducer and activator of transcription 2 C terminal

    2. XM_030822431.1 → XP_030678291.1  signal transducer and activator of transcription 2 isoform X2

      UniProtKB/TrEMBL
      A0A2I3G1P6
      Conserved Domains (5) summary
      cd10373
      Location:549 → 699
      SH2_STAT2; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 2 proteins
      smart00964
      Location:2 → 124
      STAT_int; STAT protein, protein interaction domain
      cd16852
      Location:141 → 312
      STAT2_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 2 (STAT2)
      cl28920
      Location:316 → 468
      STAT_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription (STAT)
      pfam12188
      Location:779 → 831
      STAT2_C; Signal transducer and activator of transcription 2 C terminal
    Nucleotide Protein
    Heading Accession and Version

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