galnt18b UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: galnt18bprovided by ZNC
Official Full Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-091014-1
See related: Ensembl:ENSDARG00000059438 AllianceGenome:ZFIN:ZDB-GENE-091014-1
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: galntl4b; si:ch1073-395o3.1
Summary: Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in brain; notochord; otic vesicle; sensory system; and ventral fin fold. Orthologous to human GALNT18 (polypeptide N-acetylgalactosaminyltransferase 18). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (66259215..66452793, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (66035348..66229185, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

z42919b (e-PCR), detects polymorphism
- UniSTS:238702

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables hexosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables polypeptide N-acetylgalactosaminyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein O-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18b; polypeptide N-acetylgalactosaminyltransferase 18

Names: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4b

XP_003199061.1

EC 2.4.1.-

XP_009301867.1

EC 2.4.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007118.7 Reference GRCz11 Primary Assembly

Range

66259215..66452793 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003199013.6 → XP_003199061.1 polypeptide N-acetylgalactosaminyltransferase 18 isoform X1

UniProtKB/TrEMBL

A0A8M1RSP0, E7F4H6

Related

ENSDARP00000077039.3, ENSDART00000082604.5

Conserved Domains (4) summary

cd02510
Location:159 → 460

pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans

cd00161
Location:473 → 600

RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...

pfam00652
Location:471 → 598

Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

pfam10111
Location:160 → 421

Glyco_tranf_2_2; Glycosyltransferase like family 2
XM_009303592.4 → XP_009301867.1 polypeptide N-acetylgalactosaminyltransferase 18 isoform X2

UniProtKB/TrEMBL

A0A8M3AUN5

Conserved Domains (4) summary

cd02510
Location:42 → 343

pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans

cd00161
Location:356 → 483

RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...

pfam00652
Location:354 → 481

Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

pfam10111
Location:43 → 304

Glyco_tranf_2_2; Glycosyltransferase like family 2