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    mir181b-2 microRNA 181b-2 [ Danio rerio (zebrafish) ]

    Gene ID: 100216529, updated on 12-Sep-2024

    Summary

    Official Symbol
    mir181b-2provided by ZNC
    Official Full Name
    microRNA 181b-2provided by ZNC
    Primary source
    ZFIN:ZDB-MIRNAG-081208-15
    See related
    Ensembl:ENSDARG00000081534 miRBase:MI0001367; AllianceGenome:ZFIN:ZDB-MIRNAG-081208-15
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mirn181b-2
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

    See mir181b-2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (53023679..53023764)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (53145100..53145185)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 6, group A, member 1a Neighboring gene uncharacterized LOC110440026 Neighboring gene microRNA 181a-2 Neighboring gene NAD kinase a Neighboring gene WD repeat domain 46

    Genomic regions, transcripts, and products

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_045219.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      CU914488
      Related
      ENSDART00000116681.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      53023679..53023764
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)