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    LOC100135807 branched-chain alpha-keto acid lipoamide acyltransferase [ Oncorhynchus mykiss (rainbow trout) ]

    Gene ID: 100135807, updated on 14-Dec-2023

    Summary

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    Gene symbol
    LOC100135807
    Gene description
    branched-chain alpha-keto acid lipoamide acyltransferase
    See related
    Ensembl:ENSOMYG00000030492
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oncorhynchus mykiss
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
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    Genomic context

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    See LOC100135807 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current USDA_OmykA_1.1 (GCF_013265735.2) 5 NC_048569.1 (56943843..56956322)
    100 previous assembly Omyk_1.0 (GCF_002163495.1) 5 NC_035081.1 (53456789..53469562)

    Chromosome 5 - NC_048569.1Genomic Context describing neighboring genes Neighboring gene cell division cycle 14Ab Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene small nucleolar RNA SNORD94 Neighboring gene hippocampus abundant transcript 1 protein Neighboring gene excitatory amino acid transporter 5-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of rainbow trout branched-chain alpha-keto acid dehydrogenase complex: inter-domain segments of the E2 component affect the overall activity. Hakozaki M, et al. Comp Biochem Physiol B Biochem Mol Biol, 2002 Jun. PMID 12031470
    2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipoic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    branched-chain alpha-keto acid lipoamide acyltransferase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001124203.1 → NP_001117675.1  branched-chain alpha-keto acid lipoamide acyltransferase

      See identical proteins and their annotated locations for NP_001117675.1

      Status: PROVISIONAL

      Source sequence(s)
      AB050595
      UniProtKB/TrEMBL
      A0A8C7SEQ4, Q8QHL7
      Related
      ENSOMYP00000065792.2, ENSOMYT00000071664.2
      Conserved Domains (4) summary
      cd06849
      Location:65 → 137
      lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
      PLN02528
      Location:66 → 495
      PLN02528; 2-oxoisovalerate dehydrogenase E2 component
      pfam00198
      Location:280 → 492
      2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
      pfam02817
      Location:174 → 206
      E3_binding; e3 binding domain

    RefSeqs of Annotated Genomes: Oncorhynchus mykiss Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USDA_OmykA_1.1 Primary Assembly

    Genomic

    1. NC_048569.1 Reference USDA_OmykA_1.1 Primary Assembly

      Range
      56943843..56956322
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials