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    c3-2 complement component C3-2 [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 100125802, updated on 9-Nov-2023

    Summary

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    Gene symbol
    c3-2
    Gene description
    complement component C3-2
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See c3-2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    49
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 1 NC_019859.2 (27845473..28015681, complement)
    102 previous assembly ASM31367v1 (GCF_000313675.1) 1 NC_019859.1 (27616240..27724028, complement)

    Chromosome 1 - NC_019859.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105354670 Neighboring gene complement component C3-1 Neighboring gene uncharacterized LOC111948068 Neighboring gene complement C3 Neighboring gene uncharacterized LOC110015450

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and linkage analysis of complement C3 and C4 genes of the Japanese medaka fish. Kuroda N, et al. Immunogenetics, 2000 Feb. PMID 10663574
    2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    complement component C3-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105083.1 → NP_001098553.1  complement component C3-2 precursor

      See identical proteins and their annotated locations for NP_001098553.1

      Status: PROVISIONAL

      Source sequence(s)
      AB025576
      UniProtKB/TrEMBL
      A0A3B3IBI8, Q9IBH0
      Conserved Domains (8) summary
      cd00017
      Location:669 → 738
      ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
      cd02896
      Location:991 → 1274
      complement_C3_C4_C5; Proteins similar to C3, C4 and C5 of vertebrate complement. The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the ...
      cd03583
      Location:1501 → 1655
      NTR_complement_C3; NTR/C345C domain, complement C3 subfamily; The NTR domain found in complement C3 is also known as the C345C domain because it occurs at the C-terminus of complement C3, C4 and C5. Complement C3 plays a pivotal role in the activation of the complement ...
      pfam00207
      Location:761 → 860
      A2M; Alpha-2-macroglobulin family
      pfam01835
      Location:130 → 231
      A2M_N; MG2 domain
      pfam07677
      Location:1389 → 1481
      A2M_recep; A-macroglobulin receptor
      pfam07678
      Location:1046 → 1276
      A2M_comp; A-macroglobulin complement component
      pfam07703
      Location:461 → 596
      A2M_N_2; Alpha-2-macroglobulin family N-terminal region

    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019859.2 Reference ASM223467v1 Primary Assembly

      Range
      27845473..28015681 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023959901.1 → XP_023815669.1  complement component C3-2 isoform X1

      UniProtKB/TrEMBL
      A0A3B3IBI8
      Conserved Domains (7) summary
      cd00017
      Location:669 → 738
      ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
      cd02896
      Location:991 → 1274
      complement_C3_C4_C5; Proteins similar to C3, C4 and C5 of vertebrate complement. The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the ...
      cd03583
      Location:1540 → 1694
      NTR_complement_C3; NTR/C345C domain, complement C3 subfamily; The NTR domain found in complement C3 is also known as the C345C domain because it occurs at the C-terminus of complement C3, C4 and C5. Complement C3 plays a pivotal role in the activation of the complement ...
      pfam00207
      Location:761 → 860
      A2M; Alpha-2-macroglobulin family
      pfam01835
      Location:130 → 231
      A2M_N; MG2 domain
      pfam07677
      Location:1389 → 1473
      A2M_recep; A-macroglobulin receptor
      pfam07703
      Location:457 → 597
      A2M_N_2; Alpha-2-macroglobulin family N-terminal region
    Nucleotide Protein
    Heading Accession and Version

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