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    PC pyruvate carboxylase [ Equus caballus (horse) ]

    Gene ID: 100052853, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PCprovided by VGNC
    Official Full Name
    pyruvate carboxylaseprovided by VGNC
    Primary source
    VGNC:VGNC:69324
    See related
    Ensembl:ENSECAG00000024887
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 12 NC_009155.3 (30478543..30568787, complement)

    Chromosome 12 - NC_009155.3Genomic Context describing neighboring genes Neighboring gene spectrin beta, non-erythrocytic 2 Neighboring gene uncharacterized LOC111775980 Neighboring gene TOP6B like initiator of meiotic double strand breaks Neighboring gene uncharacterized LOC111775981 Neighboring gene Ras converting CAAX endopeptidase 1 Neighboring gene leucine rich repeat and fibronectin type III domain containing 4 Neighboring gene chromosome 12 C11orf86 homolog Neighboring gene uncharacterized LOC111775982 Neighboring gene synaptotagmin 12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009155.3 Chromosome 12 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyruvate carboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pyruvate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyruvate carboxylase, mitochondrial
    Names
    mitochondrial pyruvate carboxylase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009155.3 Reference EquCab3.0 Primary Assembly

      Range
      30478543..30568787 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023654520.1 → XP_023510288.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    2. XM_023654522.1 → XP_023510290.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    3. XM_023654521.1 → XP_023510289.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    4. XM_023654525.1 → XP_023510293.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Related
      ENSECAP00000022503.4, ENSECAT00000026917.4
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    5. XM_023654523.1 → XP_023510291.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    6. XM_023654526.1 → XP_023510294.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    7. XM_023654527.1 → XP_023510295.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Related
      ENSECAP00000052257.2, ENSECAT00000074179.2
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    8. XM_023654524.1 → XP_023510292.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Related
      ENSECAP00000022492.4, ENSECAT00000026905.4
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    9. XM_023654528.1 → XP_023510296.1  pyruvate carboxylase, mitochondrial

      UniProtKB/TrEMBL
      A0A5F5PVH8
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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