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    CYP85A1 6-deoxocastasterone oxidase [ Solanum lycopersicum (tomato) ]

    Gene ID: 100037489, updated on 1-Nov-2024

    Summary

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    Gene symbol
    CYP85A1
    Gene description
    6-deoxocastasterone oxidase
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Solanum lycopersicum
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Solanum subgen. Lycopersicon
    Also known as
    CYP85; Dwarf; LeCYP85A1
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    Genomic context

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    See CYP85A1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_09 current SLM_r2.1 (GCF_036512215.1) 2 NC_090801.1 (67368687..67371559)
    103 previous assembly SL3.0 (GCF_000188115.4) 2 NC_015439.3 (51681494..51684337)

    Chromosome 2 - NC_090801.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101252543 Neighboring gene PI-PLC X domain-containing protein At5g67130 Neighboring gene probable UDP-arabinopyranose mutase 1 Neighboring gene tRNA (guanine(26)-N(2))-dimethyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DWARF overexpression induces alteration in phytohormone homeostasis, development, architecture and carotenoid accumulation in tomato. Li XJ, et al. Plant Biotechnol J, 2016 Mar. PMID 26383874
    2. Metabolic changes in fruits of the tomato dx mutant. Lisso J, et al. Phytochemistry, 2006 Oct. PMID 16930643
    3. Patterns of Dwarf expression and brassinosteroid accumulation in tomato reveal the importance of brassinosteroid synthesis during fruit development. Montoya T, et al. Plant J, 2005 Apr. PMID 15807787
    4. The tomato DWARF enzyme catalyses C-6 oxidation in brassinosteroid biosynthesis. Bishop GJ, et al. Proc Natl Acad Sci U S A, 1999 Feb 16. PMID 9990098, Free PMC Article
    5. The tomato Dwarf gene isolated by heterologous transposon tagging encodes the first member of a new cytochrome P450 family. Bishop GJ, et al. Plant Cell, 1996 Jun. PMID 8672892, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the function of DWARF (DWF), the key BR biosynthetic gene in tomato, in the regulation of plant growth and architecture, phytohormone homeostasis and fruit development, is reported.
      Title: DWARF overexpression induces alteration in phytohormone homeostasis, development, architecture and carotenoid accumulation in tomato.
    2. Mutations in the D gene result in altered levels of sugar, starch, and amino acid metabolism. [DWARF]
      Title: Metabolic changes in fruits of the tomato dx mutant.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in brassinosteroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in brassinosteroid homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    6-deoxocastasterone oxidase
    Names
    C6-oxidase
    castasterone synthase CYP85A1
    cytochrome P450 85A1
    cytochrome P450 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001247334.2 → NP_001234263.1  6-deoxocastasterone oxidase isoform 1

      See identical proteins and their annotated locations for NP_001234263.1

      Status: VALIDATED

      Source sequence(s)
      AEKE03003138, DQ374447
      UniProtKB/Swiss-Prot
      Q43147
      UniProtKB/TrEMBL
      Q0NZY6
      Conserved Domains (1) summary
      PLN02774
      Location:13 → 464
      PLN02774; brassinosteroid-6-oxidase

    2. NM_001329859.1 → NP_001316788.1  6-deoxocastasterone oxidase isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK324524
      UniProtKB/TrEMBL
      Q0NZZ1
      Conserved Domains (1) summary
      cl12078
      Location:13 → 436
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_036512215.1-RS_2024_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference SLM_r2.1 Primary Assembly

    Genomic

    1. NC_090801.1 Reference SLM_r2.1 Primary Assembly

      Range
      67368687..67371559
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_019211956.3 → XP_019067501.1  6-deoxocastasterone oxidase isoform X2

      UniProtKB/TrEMBL
      Q0NZZ0

    2. XM_069293092.1 → XP_069149193.1  6-deoxocastasterone oxidase isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q43147.1 GenPept UniProtKB/Swiss-Prot:Q43147

    Gene LinkOut

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    Molecular Biology Databases