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Butler M, Urosevic S, Desai P, et al. Treatment for Bipolar Disorder in Adults: A Systematic Review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018 Aug. (Comparative Effectiveness Review, No. 208.)
Table 1FDA-approved medications for bipolar disorder
| Drug Type | Generic Name First Date Approved | FDA –Listed Trade Name (Pharmaceutical Co.) | Manic | Mixed (Mania/Depression) | Mainte-nance | Depression |
|---|---|---|---|---|---|---|
| Salts | Lithium 1970 | X | X | |||
| Atypical Antipsychotics | Aripiprazole 2004 | Abilify (Otsuka) | X | X | X | |
| Asenapine 2015 | Saphris (Organon Sub Merck) | X | X | |||
| Cariprazine 2015 | Vraylar (Forest | |||||
| Lurasidone 2013 | Latuda (Sunovion Pharms) | X | ||||
| Olanzapine* 2000 | Zyprexa (Lilly) | X | X | X | ||
| Olanzapine/fluoxetine combination* 2012 | Symbyax (Lilly) | X | ||||
| Quetiapine 2004 | Seroquel (AstraZeneca) | X | X | |||
| Risperidone 2003 | Risperdal (Janssen Pharm) | X | X | |||
| Ziprasidone 2004 | Geodon (Pfizer) | X | X | |||
| Anticonvulsants | Carbamazepine* 2004 | Carbetrol (Shire), Epitol (TEVA), Equetro (Validus Pharms), Tegretol (Novartis), Teril (Taro) | X | X | ||
| Lamotrigine* 2003 | Lamictal (GlaxoSmithKline) | X | ||||
| Divalproex sodium* or valproate 1995 | Depakote (ABBVIE) | X | ||||
| Lamotrigine* 2003 | Lamictal (GlaxoSmithKline) | X |
- *
Generic forms are available. FDA=Food and Drug Administration
- Table 1, FDA-approved medications for bipolar disorder - Treatment for Bipolar D...Table 1, FDA-approved medications for bipolar disorder - Treatment for Bipolar Disorder in Adults: A Systematic Review
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