Kidney transplant response to calcineurin inhibitor-free immunosuppression using sirolimus
Summary:
Analysis of kidneys from adult renal transplant recipients subjected to calcineurin inhibitor-free immunosuppression using sirolimus. Patients treated with sirolimus have a lower prevalence of chronic allograft nephropathy compared to those treated with cyclosporine, a calcineurin inhibitor.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Flechner SM, Kurian SM, Solez K, Cook DJ et al. De novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function at two years. Am J Transplant 2004 Nov;4(11):1776-85. PMID: 15476476