Estradiol effect on osteosarcoma cells expressing estrogen receptor alpha or beta: time course
Summary:
Expression profiling of U2OS osteosarcoma cells after treatment with 17beta-estradiol (E2) for various lengths of time up to 48 hours. U2OS transfected with either estrogen receptor (ER) alpha or beta. Results identify signaling pathways in bone regulated by E2 through ERalpha and ERbeta.
GPL91:
[HG_U95A] Affymetrix Human Genome U95A Array
Citation:
Stossi F, Barnett DH, Frasor J, Komm B et al. Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human osteosarcoma cells: distinct and common target genes for these receptors. Endocrinology 2004 Jul;145(7):3473-86. PMID: 15033914
