Insulitis: comparison of innocuous and destructive forms
Summary:
Analysis of CD4+ automimmune T and CD45+ hematopoeitic cells from non-obese diabetic (NOD) and C57BL/6-H-2 g7 transgenics with the BDC2.5 T cell receptor (TCR) from a diabetogenic T cell. BDC2.5 TCR in NOD and in C57BL/6-H-2 g7 results in innocuous and destructive insulitis respectively.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Poirot L, Benoist C, Mathis D. Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity. Proc Natl Acad Sci U S A 2004 May 25;101(21):8102-7. PMID: 15141080
