Expression profiling of brain hippocampi from 22 postmortem subjects with Alzheimer's disease (AD) at various stages of severity. 7, 8, and 7 subjects diagnosed with incipient, moderate, and severe AD respectively. Results provide insight into mechanisms underlying the early pathogenesis of AD.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Blalock EM, Geddes JW, Chen KC, Porter NM et al. Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc Natl Acad Sci U S A 2004 Feb 17;101(7):2173-8. PMID: 14769913