Interferon-alpha effect on monocytes primed with interferon-gamma
Summary:
Expression profiling of monocytes cultured for 2 days with 150 pg/ml interferon (IFN) gamma and then stimulated with 25 ng/ml of IFN-alpha. Monocytes obtained from 3 donors. Results provide insight into mechanisms underlying the enhanced response of IFN primed monocytes to cytokines.
GPL8300:
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citation:
Tassiulas I, Hu X, Ho H, Kashyap Y et al. Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors. Nat Immunol 2004 Nov;5(11):1181-9. PMID: 15467722
