Short-term high fat diet effect on epididymal adipose fractions: time course
Summary:
Analysis of primary adipocytes from epididymis of C57BL/6J males fed a 60% high fat diet (HFD) for up to 7 days to induce obesity. Results provide insight into the molecular mechanisms underlying insulin resistance in adipose tissues during early obesity.
Kim JI, Huh JY, Sohn JH, Choe SS et al. Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation. Mol Cell Biol 2015 May;35(10):1686-99. PMID: 25733684