Type I angiotensin II receptor antagonist valsartan effect on mitral regurgitation males: left atria
Summary:
Analysis of left atria of mitral regurgitation (MR) males treated with valsartan one week before surgery and then daily after surgery. Valsartan is a type I angiotensin II receptor blocker. Results provide insight into molecular mechanisms underlying atrial myocardial remodeling in MR subjects.
Chen MC, Chang JP, Chang TH, Hsu SD et al. Unraveling regulatory mechanisms of atrial remodeling of mitral regurgitation pigs by gene expression profiling analysis: role of type I angiotensin II receptor antagonist. Transl Res 2015 May;165(5):599-620. PMID: 25500755