Estradiol effect on uterus of EAAE estrogen receptor α DNA-binding-deficient model
Summary:
Analysis of uteri from ovariectomized, EAAE ERα DNA-binding domain mutants collected 2hrs after estradiol injection. The EAAE mouse has an ERα null-like female reproductive tract phenotype. Results provide insight into the ability of EAAE ERα to mediate transcriptional responses in the uterus.
Hewitt SC, Li L, Grimm SA, Winuthayanon W et al. Novel DNA motif binding activity observed in vivo with an estrogen receptor α mutant mouse. Mol Endocrinol 2014 Jun;28(6):899-911. PMID: 24713037
