Peroxisome proliferator-activated receptor β/δ agonist and hypoxia effects on umbilical vein endothelial cells
Summary:
Analysis of HUVECs stimulated with two important angiogenic stimuli: peroxisome proliferator-activated receptor (PPAR) β/δ agonist and hypoxia. Results provide insight into possible synergistic molecular interactions between the PPAR β/δ and hypoxia-inducible factor (HIF) 1 signaling pathways.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Inoue T, Kohro T, Tanaka T, Kanki Y et al. Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements. Genome Biol 2014 Apr 10;15(4):R63. PMID: 24721177