Glucosamine treatment effect on KMH2 malignant lymphocytes
Summary:
Analysis of Hodgkin lymphoma-derived cell line KMH2 treated with glucosamine (GlcN) for 24 hr. GlcN induces the posttranslational modification of proteins with O-linked β-N-acetylglucosamine (O-GlcNAc). Results provide insight into the molecular mechanisms activated following GlcN intake.
GPL11532:
[HuGene-1_1-st] Affymetrix Human Gene 1.1 ST Array [transcript (gene) version]
Citation:
Carvalho AS, Ribeiro H, Voabil P, Penque D et al. Global mass spectrometry and transcriptomics array based drug profiling provides novel insight into glucosamine induced endoplasmic reticulum stress. Mol Cell Proteomics 2014 Dec;13(12):3294-307. PMID: 25128556
