DataSet Record GDS5380: Expression Profiles Data Analysis Tools Sample Subsets
Title: Sodium tungstate effect on insulin receptor substrate 2 knockout mice: pancreatic islets
Cluster AnalysisGDS5380 Cluster Image
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Summary: Analysis of pancreatic islets from insulin receptor substrate 2 (Irs2) knockouts treated with anti-diabetic compound sodium tungstate for 21 days. Tungstate normalizes glucose tolerance in the Irs2 -/- animals. Results provide insight into the molecular effects of tungstate on pancreatic β-cells.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Oliveira JM, Rebuffat SA, Gasa R, Burks DJ et al. Tungstate promotes β-cell survival in Irs2-/- mice. Am J Physiol Endocrinol Metab 2014 Jan 1;306(1):E36-47. PMID: 24253047
Reference Series: GSE43620 Sample count: 8
Value type: transformed count Series published: 2014/01/19