Negative elongation factor B subunit deficiency effect on the heart
Summary:
Analysis of heart left ventricles from mutants lacking the B subunit of negative elongation factor (NELF). NELF is a regulator of RNA polymerase II pausing. Results provide insight into the role of NELF in myocardial function.
Pan H, Qin K, Guo Z, Ma Y et al. Negative elongation factor controls energy homeostasis in cardiomyocytes. Cell Rep 2014 Apr 10;7(1):79-85. PMID: 24656816
