Rheumatoid arthritis and response to anti-TNF therapy: blood
Summary:
Analysis of blood from rheumatoid arthritis (RA) patients prior to anti-TNF therapy. Response of patients to anti-TNF therapy assessed after 14 weeks. Results identify a gene expression signature for predicting the response to anti-TNF therapy.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Bienkowska JR, Dalgin GS, Batliwalla F, Allaire N et al. Convergent Random Forest predictor: methodology for predicting drug response from genome-scale data applied to anti-TNF response. Genomics 2009 Dec;94(6):423-32. PMID: 19699293