Hoxa1 deficiency effect on rhombomere regions 3 to 5
Summary:
Analysis of rhombomere regions 3 to 5 from embryos lacking the homeobox protein Hoxa1. Hoxa1 is necessary for the development of the brainstem, inner ear and heart. Results identify the role of Hoxa1 during embryogenesis.
Makki N, Capecchi MR. Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development. Dev Biol 2011 Sep 15;357(2):295-304. PMID: 21784065