Silica nanoparticle effect on lung adenocarcinoma epithelial A549 cells
Summary:
Analysis of A549 cells treated with SiO2 NPs (diameters of 9nm and 18nm) and examined after 3hr and 22hr recovery times. Coated nanomaterials (e.g., SiO2 NPs) agglomerate less and are, thus, more easily inhalable. Results provide molecular insight into molecular basis of nanotoxicological effects.
GPL6480:
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Citation:
Fede C, Millino C, Pacchioni B, Celegato B et al. Altered gene transcription in human cells treated with Ludox® silica nanoparticles. Int J Environ Res Public Health 2014 Aug 28;11(9):8867-90. PMID: 25170680
