Type 2 diabetic obese patients: visceral adipose tissue CD14+ cells
Summary:
Analysis of visceral adipose tissue CD14+ cells isolated from obese, type 2 diabetic patients. Obesity is marked by changes in the immune cell composition of adipose tissue. Results provide insight into the molecular basis of proinflammatory cytokine production in obesity-linked type 2 diabetes.
Dalmas E, Venteclef N, Caer C, Poitou C et al. T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes. Diabetes 2014 Jun;63(6):1966-77. PMID: 24520123