FAT1 depletion effect on astrocyte and glioma cell lines
Summary:
Analysis of astrocyte and glioma cells depleted for FAT1. FAT1 encodes a cadherin-like protein. Results provide insight into the role of FAT1 in cancer development.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Morris LG, Kaufman AM, Gong Y, Ramaswami D et al. Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. Nat Genet 2013 Mar;45(3):253-61. PMID: 23354438