Pseudomonas aeruginosa sphR deficient mutant response to lung surfactant
Summary:
Analysis of P. aeruginosa sphR null mutants grown in media containing lung surfactant. P. aeruginosa is an opportunistic pathogen of the human lung. SphR is an AraC-family transcription factor. Results provide insight into the role of sphR in P. aeruginosa infections in the lung.
LaBauve AE, Wargo MJ. Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung. PLoS Pathog 2014 Jan;10(1):e1003889. PMID: 24465209
