Lysophosphatidic acid effect on breast and prostate cancer cell lines
Summary:
Analysis of MDA-MB-231, MCF7 and PC3 cells treated with lysophosphatidic acid (LPA). LPA activates six different G protein-coupled receptors (LPA receptors 1-6). Results provide insight into LPA-induced genes among three unrelated cancer cell lines expressing different patterns of LPA receptors.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
David M, Sahay D, Mege F, Descotes F et al. Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers. PLoS One 2014;9(5):e97771. PMID: 24828490
