High-grade serous ovarian cancer resistant to platinum-based chemotherapy
Summary:
Analysis of tumors from high-grade serous ovarian cancer patients resistant or sensitive to platinum-based chemotherapy. Tumor samples collected prior to chemotherapy. Results identify a gene expression profile associated with intrinsic chemotherapy resistance.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Koti M, Gooding RJ, Nuin P, Haslehurst A et al. Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer. BMC Cancer 2013 Nov 16;13:549. PMID: 24237932
