Pancreatic cancer-induced cachexia model: muscle, liver and white adipose tissue
Summary:
Analysis of 3 tissue types from a pancreatic cancer-induced cachexia model. Cancer cachexia syndrome is associated with severe wasting in advanced-stage cancer. Results provide insight into molecular mechanisms underlying muscle, liver and white adipose tissue cachexia.
Gilabert M, Calvo E, Airoldi A, Hamidi T et al. Pancreatic cancer-induced cachexia is Jak2-dependent in mice. J Cell Physiol 2014 Oct;229(10):1437-43. PMID: 24648112