Glioblastoma cells response to Focal Adhesion Kinase Inhibitor Y15 and Temozolomide
Summary:
Analysis of DBTRG glioblastoma cells treated with FAK inhibitor Y15, and U87 glioblastoma cells treated with Y15 and chemotherapy drug temozolomide. Results provide insight into molecular mechanisms underlying the synergistic inhibitory effect of Y15 and temozolomide on glioblastoma growth.
Huang G, Ho B, Conroy J, Liu S et al. The microarray gene profiling analysis of glioblastoma cancer cells reveals genes affected by FAK inhibitor Y15 and combination of Y15 and temozolomide. Anticancer Agents Med Chem 2014 Jan;14(1):9-17. PMID: 23387973
