Analysis of IκBζ-deficient peritoneal macrophages (PMψ) stimulated with LPS. These PMψ exhibit impaired secretion of monocyte chemoattractant protein 1 (MCP-1) which is critical for directing monocyte migration to inflammation sites. Results provide insight into role of IκBζ in Mψ physiology.
Hildebrand DG, Alexander E, Hörber S, Lehle S et al. IκBζ is a transcriptional key regulator of CCL2/MCP-1. J Immunol 2013 May 1;190(9):4812-20. PMID: 23547114
