Analysis of colonic intestinal explants stimulated with PMA/IO to induce pro-inflammatory conditions then incubated with various commensal lactobacilli strains. Results provide insight into the molecular basis of probiotic attenuation of inflammatory processes in a colon organ culture model.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Bäuerl C, Llopis M, Antolín M, Monedero V et al. Lactobacillus paracasei and Lactobacillus plantarum strains downregulate proinflammatory genes in an ex vivo system of cultured human colonic mucosa. Genes Nutr 2013 Mar;8(2):165-80. PMID: 22669626
