Analysis of lens from ICR embryos at 3 key developmental stages in the transition from E10.5 lens placode invagination to E12.5 lens primary fiber cell differentiation and matched whole embryo body (WB, minus ocular tissue) controls. Results provide insight into molecular basis of lens development.
Lachke SA, Ho JW, Kryukov GV, O'Connell DJ et al. iSyTE: integrated Systems Tool for Eye gene discovery. Invest Ophthalmol Vis Sci 2012 Mar;53(3):1617-27. PMID: 22323457