p53 mutations in microsatellite-stable, stage III colorectal cancer
Summary:
Analysis of Stage III CRCs exhibiting microsatellite-stable (MSS) and mutant p53 phenotypic features. p53 mutations are associated with higher Stage III MSS CRC mortality than p53 wild-type phenotypes. Results provide further insight into the prognostic value of p53 mutations in Stage III MSS CRCs.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Katkoori VR, Shanmugam C, Jia X, Vitta SP et al. Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomas. PLoS One 2012;7(1):e30020. PMID: 22276141