Transcription factor pancreatic and duodenal homeobox 1 deficiency effect on proximal small intestine
Summary:
Analysis of mature proximal small intestine with intestinal epithelium-specific pancreatic and duodenal homeobox 1 (Pdx1) inactivation. Pdx1 is essential for regulating pancreatic development and maintaining proper islet function. Results provide insight into role of Pdx1 in duodenum.
Chen C, Sibley E. Expression profiling identifies novel gene targets and functions for Pdx1 in the duodenum of mature mice. Am J Physiol Gastrointest Liver Physiol 2012 Feb 15;302(4):G407-19. PMID: 22135308
